This recipe explains, on using .NET standard extension methods in full framework app similar to one in .NET Core application. This also helps in leveraging a number of Steeltoe extension methods.
Add a class in the root of the application or under App_Start, called BootConfig.cs
Add the below nuget packages (preferably latest versions)
Add the below code into the class
    public class BootConfig
    {
        static IHost host;
        public static void Configure(string environment)
        {
            host = new HostBuilder()
                .ConfigureAppConfiguration((builderContext, configBuilder) =>
                {
                    //Add your IConfiguration builder extensions methods here
                })
                .ConfigureServices((builderContext, services) =>
                {
                    //Add your IServiceCollection builder extensions methods here
                })
                .ConfigureLogging((context, loggerFactory) =>
                {
                    //Add your ILoggerFactory extensions methods here
                })
                .Build();
        }
        public static T GetService<T>()
        {
            return host?.Services?.GetService<T>();
        }
    }
In Application_Start method of Global.asax.cs class, call the Configure method, which will create DI container, inject configurations and even configure logging as provided
    public void Application_Start(object sender, EventArgs e)
    {
        ...
        BootConfig.Configure("development"); //pass in the enviroment variable here (hardcoded for sample purposes only)
    }
You can also access the registered services using BootConfig.GetService<T>() method, anywhere from the applications.
Note: In case the application uses any DI framework, you can populate these services into their containers, where you may no need the
BootConfig.GetService<T>()method.